Partha S. Ray, Ph.D.
Department of Chemistry
University of West Georgia
Carrollton, GA 30118-4150
(678) 839-6023
POSITION DEPARTMENT INSTITUTION/COMPANY PERIOD
Professor Chemistry University of West Georgia Aug 06- current
Associate Professor Chemistry University of West Georgia Aug 00-July 06
Assistant Professor Chemistry University of Memphis Aug 93-May 00
Research Chemist Chemistry FMC Corporation (Princeton, NJ) Jan 88-July 93
Postdoc Research Associate Chemistry Princeton University Oct 85-Dec 87
Medicinal Research Chemist Medicinal Chemistry G.D. Searle (High Wycombe, UK) April 83-Sept 85
DEGREE DISCIPLINE INSTITUTION YEAR
Ph.D. Synthetic Organic Chemistry The University of East Anglia, UK 1982
M.Sc. Physical Organic Chemistry The University of East Anglia 1980
B.Sc. Chemistry (with Honors) The University of East Anglia 1978
Publications & Patents
36. J. Chambers, B. Eaves, D. Parker, R. Claxton, P.S. Ray, and S.J. Slattery, “Inductive Influence of 4’-Terpyridyl Substituents on Redox and Spin State Properties of Iron(II) and Cobalt(II) Bis-Terpyridyl Complexes,” Inorganica Chimica Acta, 2006, 359, 2400-2406.
35. N.E. Huddleston, J.L. Harris, H.L. Nguyen, and P.S. Ray, “Synthesis of a 2-Amino-4-chloro-6,9-bis-(2,4-dimethoxybenzyl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-e][1,4]diazepine: A Potentially Useful Intermediate to Pyrimido[4,5-e][1,4]diazepine-Based Folates,” Heterocyclic Communications, 2004, 10, 405-406.
34. D. P. Parker, S. A. Hughes, D. L. Parker, and P. S. Ray, “An Unexpected Dimer Formation From a 4-(2-Amino-ethylamino)-5-formylpyrimidine Intermediate,” Heterocyclic Communications, 2002, 8, 419-422.
33. D. L. Parker, D. P. Parker, A. L. Kimball, B. K. Ayida, and P. S. Ray, “Progress Towards the Synthesis of Pyrimidodiazepine-Based Folates as Potential Inhibitors of Glycinamide Ribionucleotide Formyltransferase” in “Chemistry and Biology of Pteridines and Folates”, Eds. S. Milstien, G. Kapatos, R. A. Levine, and B. Shane, Kluwer Academic Publishers, Boston, p 427-431, 2002.
32. M. W. Read, M. L. Miller, and P. S. Ray , “Synthesis of N-{[4-(2-Amino-4(3H)-oxo-5,6,7,8,-tetrahydropyrimido-[4,5-b]azepin-6-yl)methyl]benzoyl}-L-glutamic Acid and two of its Conformationally- Restricted Analogs,”Tetrahedron, 1999, 55, 373-392.
31. N. A. Ayers, O. W. Nadeau, M. W. Read, P. S. Ray, and G. M. Carlson, "Effector-Sensitive Crosslinking of Phosphorylase-b Kinase by the Novel Crosslinker, 4-Phenyl-1,2,4-triazoline-3,5-dione," Biochemical Journal, 1998, 331, 137-141.
30. R. N. Henrie II, C. J. Peake, T. G. Cullen, M. K. Chaguturu, P. S. Ray, B. D. Bennett," 2,4-Diamino-5,6-disubstituted- and 5,6,7-Trisubstituted 5-Deazapteridines as Insecticides," United States Patent: 5,710,157; January 20, 1998.
29. S. D. Selvidge III, J. Jang, and P. S. Ray, "Synthesis of 5-Formyluridines,"Nucleosides and Nucleotides, 1997, 16, 2019-2024.
28. M. L. Miller and P. S. Ray, "A Convenient Synthesis of 2,2,4-Trimethylcyclohexane-1,3-dione: A Useful Presursor for the Taxoid A Ring," Synthetic Communications, 1997, 27, 3991-3996.
27. M. L. Miller and P. S. Ray, "Synthesis of 4-[8-Amino-6-benzyl-10(9H)-oxo-4,5-dihydro-(6H)- isoxazolo[3,4-d]pyrimido[4,5-b]azepin-3-yl]benzoyl-L-glutamic Acid. A Novel Pyrimidoazepine-Based Folic Acid Derivative," Heterocycles, 1997, 45, 501-506.
26. K. L. Smith and P. S. Ray, "Synthesis of 2,4-Dimethylthiobenzo[c][2,7]naphthyridin-5(6H)-one: A Potentially Useful Intermediate for the Synthesis of Pyridoacridine Alkaloids," Heterocycles, 1997, 45, 11-14.
25. R. N. Henrie II, C. J. Peake, T. G. Cullen, M. K. Chaguturu, P. S. Ray, B. D. Bennett,"Insecticidal 5-Substituted-2,4-diaminopyrimidine Derivatives," United States Patent: 5,627189; May 6, 1997.
24. R. N. Henrie II, C. J. Peake, T. G. Cullen, M. K. Chaguturu, P. S. Ray, B. D. Bennett,"2,4-Diamino-5,6-disubstituted- and 5,6,7-Trisubstituted 5-Deazapteridines as Insecticides," United States Patent: 5,593,998; January 14, 1997.
23. M. L. Miller and P. S. Ray, "Synthesis of 5-Amino-9-benzyl-6-formyl-4-methoxy-2-pivaloylamino-7,8-dihydropyrimido[4,5-b]azepine. A Potentially Useful Intermediate Towards the Synthesis of Pyrimidoazepine Based Folic Acid Derivatives," J. Heterocyclic Chem., 1996, 33, 259-263.
22. M. L. Miller and P. S. Ray, "An Intramolecular 1,3-Dipolar Cycloaddition Approach to a Pyrimidoazepinone Derivative. A Potentially Useful Intermediate Towards the Synthesis of Pyrimidoazepine Based Folic Acid Derivatives,"Tetrahedron, 1996, 52, 5739-5744.
21. R. N. Henrie II, C. J. Peake, T. G. Cullen, M. K. Chaguturu, P. S. Ray, B. D. Bennett,"Insecticidal 5-Substituted-2,4-diaminopyrimidine Derivatives," United States Patent: 5,587,379; December 24, 1996.
20. R. N. Henrie II, C. J. Peake, T. G. Cullen, M. K. Chaguturu, P. S. Ray, B. D. Bennett,"2,4-Diamino-5,6-disubstituted- and 5,6,7-Trisubstituted 5-Deazapteridines as Insecticides," United States Patent: 5,547,954; August 20, 1996.
19. R. N. Henrie II, C. J. Peake, T. G. Cullen, M. K. Chaguturu, P. S. Ray, B. D. Bennett,"2,4-Diamino-5,6-disubstituted- and 5,6,7-Trisubstituted 5-Deazapteridines as Insecticides," United States Patent: 5,532,370; July 2, 1996.
18. R. N. Henrie II, C. J. Peake, T. G. Cullen, M. K. Chaguturu, P. S. Ray, B. D. Bennett,"Insecticidal 5-Substituted-2,4-diaminopyrimidine Derivatives," United States Patent: 5,521,192; May 28, 1996.
17. M. W. Read and P. S. Ray, "Synthesis of a 1,8-Naphthyridin-5-one Derivative via an Intramolecular 1,3- Dipolar Cycloaddition Reaction," J. Heterocyclic Chem., 1995, 32, 1595-1597.
16. P. S. Ray and M. J. Manning, "A New Synthesis of 2-Acylaminoisoquinolin-1(2H)-ones From 2-Vinylbenzoic Acid," Heterocycles, 1994, 38, 1361-1365.
15. R. N. Henrie II, C. J. Peake, T. G. Cullen, M. K. Chaguturu, P. S. Ray, B. D. Bennett, "Insecticidal 5-Substituted-2,4-diaminopyrimidine Derivatives," International Publication No: WO 94/12032; 9 June 1994.
14. R. N. Henrie II, C. J. Peake, T. G. Cullen, M. K. Chaguturu, P. S. Ray, B. D. Bennett,"Insecticidal Substituted-2,4-diaminoquinazolines," International Publication No: WO 94/18980; 1 September 1994.
13. P. S. Ray, J. Buote, C. A. Webster and M. J. Manning, "Synthesis of 7,8,9,10-Tetrahydropyridazino[1,2-a][1,2,4]benzotriazin-6-one Derivatives. A Novel Heterocyclic System," J. Heterocyclic Chem., 1993, 30, 45-48.
12. G. A. Meier, I. R. Silverman, P. S. Ray, T. G. Cullen, S. F. Ali, F. L. Marek and C. A. Webster, "Insecticidal Dihydropyrazoles with Reduced Lipophilicity," ACS Symposium Series No. 504, Synthesis and Chemistry of Agrochemicals III, Ed. Baker et. al., American Chemical Society, 1992, Chapter 28, 313-326.
11. E. C. Taylor and P. S. Ray, "An Intramolecular 1,3-Dipolar Cycloaddition Approach to 5,6,7,8-Tetrahydro-(4-ethoxy-6-hydroxymethyl-2-pivaloylamino)- 5-deazapteridin -5(8H)-one, A Potentially Useful Intermediate to 5-Deaza and 5,10-Dideaza-5,6,7,8-tetrahydrofolic Acid Analogs," Heterocycles, 1991, 32, 1327-1340.
10. E. C. Taylor and P. S. Ray, "A Novel Synthetic Approach to C-6 Carbon-Substituted Pterins via Intermolecular 1, 3-Dipolar Cycloaddition Reactions," J. Org. Chem., 1991, 56, 1812-1816.
9. P. S. Ray and A. A. Jaxa-Chamiec, "Novel Thymidine Analogs via Reaction of Unprotected 5'-Deoxy-5'-iodothymidine with Dianions," Heterocycles, 1990, 31, 1777-1780.
8. P. S Ray and R. F. Hank, "A Convenient Synthesis of 1-Aryl-3-methyl-1,2,4-triazolin-5-ones From the Reaction Between Acetone Arylhydrazones and Acetyl Isocyanate," J. Heterocyclic Chem., 1990, 2017- 2020.
7. E. C. Taylor, P. S. Ray, I. S. Darwish and R. Dotzer,"Synthetic Studies on the Molybdenum Cofactor," Chemistry and Biology of Pteridines, Proceedings of the Ninth International Symposium on Pteridines and Folic Acid Derivatives, H.-Ch. Curtis, S. Ghisla, N. Blau, Eds.; Walter de Gruyter, Berlin, 1990, p 67-72.
6. E. C. Taylor, P. S. Ray, I. S. Darwish, J. L. Johnson and K. V. Rajagopalan, "Studies on the Molybdenum Cofactor. Determination of the Structure and Absolute Configuration of Form A," J. Am. Chem. Soc., 1989, 111, 7664-7665.
5. E. C. Taylor and P. S. Ray, "A Convenient Synthetic Approach to 10-Deazaaminopterin and 10-Deazafolic Acid," J. Org. Chem., 1988, 53, 35-35.
4. E. C. Taylor and P. S. Ray, "A Convenient Synthesis of 6-Formylpterin," Syn. Comm., 1987, 17, 1865- 1868.
3. E. C. Taylor and P. S. Ray,"A New and Unequivocal Route to C-6 Carbon-Substituted Pterins and Pteridines," J. Org. Chem., 1987, 52, 3997-4000.
2. R. C. Cookson and P. S. Ray, "A New Synthesis of Macrocyclic Keto-Lactones via Ring Expansion of 2-(3-Hydroxypropyl)-2-nitrocycloalkanones," Tetrahedron Lett., 1982, 23, 3521-3524.
1. A. McKillop, A. Henderson, P. S. Ray, C. Avenando, E.G. Molinero,"Heterocyclic Synthesis Using Ethyl Carboethoxyformimidate," Tetrahedron Lett., 1982, 23, 3357-3360.
31. November 11, 2004: P.S. Ray, “Progress Towards the Synthesis of Pyrimidodiazepine-Based Folates as Potential Inhibitors of Glycinamide Ribonucleotide Formyltransferase”. 56th Southeast Regional Meeting of the American Chemical Society, Durham, North Carolina; Paper no. 198.
30. November 18, 2003: P. S. Ray, “Progress Towards the Synthesis of Pyrimidodiazepine-Based Folates as Potential Antitumor Agents”. 55th Southeast Regional Meeting of the American Chemical Society, Atlanta, Georgia; Paper no. 625.
29. November 14, 2002: P.S. Ray, “Progress Towards the Synthesis of Pyrimidodiazepine-Based Folates as Potential Inhibitors of Glycinamide Ribonucleotide Formyltransferase”. 54th Southeast Regional Meeting of the American Chemical Society, Charleston, South Carolina. Paper no.185.
28. November 8, 2002: Georgia State University, Department of Chemistry, Atlanta, Georgia. Title: Synthesis of Pyrimidoazepine and Diazepine-Based Folates as Potential Antitumor Agents.
27. September 23, 2001: D. L. Parker, D. P. Parker, A. L. Kimball, B. K. Ayida, and P. S. Ray, “Progress Towards the Synthesis of Pyrimidodiazepine-Based Folates as Potential Inhibitors of Glycinamide Ribonucleotide Formyltransferase”. 53rd Southeast Regional Meeting of the American Chemical Society, Savannah, Georgia; Paper no. 370.
26. June 18, 2001: D. L. Parker, D. P. Parker, A. L. Kimball, B. K. Ayida, and P. S. Ray, “Progress Towards the Synthesis of Pyrimidodiazepine-Based Folates as Potential Inhibitors of Glycinamide Ribonucleotide Formyltransferase” 12th International Symposium on the Chemistry and Biology of Pteridines and Folates, National Institutes of Health, Bethesda, Maryland.
25. February 2000: Ohio Northern University, Ada, Ohio. Department of Chemistry. Title: Synthesis and Antitumor Properties of Pyrimidoazepine-Based Tetrahydrofolic Acid Derivatives
24. January 2000: Bates College, Department of Chemistry, Lewiston, Maine. Title: Synthesis and Antitumor Properties of Pyrimidoazepine-Based Tetrahydrofolic Acid Derivatives
23. January 2000: Florida Institute of Technology, Department of Chemistry, Melbourne, Florida.
Title: Synthesis and Antitumor Properties of Pyrimidoazepine-Based Tetrahydrofolic Acid Derivatives
22. January 2000: University of West Georgia, Department of Chemistry, Carrollton, Georgia. Title: Synthesis and Antitumor Properties of Pyrimidoazepine-Based Tetrahydrofolic Acid Derivatives
21. December 1999: Denison University, Department of Chemistry, Granville, Ohio. Title: Synthesis and Antitumor Properties of Pyrimidoazepine-Based Tetrahydrofolic Acid Derivatives
20. December 1999: New Mexico Institute of Mining and Technology, Department of Chemistry, Socorro, New Mexico. Title: Synthesis and Antitumor Properties of Pyrimidoazepine-Based Tetrahydrofolic Acid Derivatives
19. September 13, 1999: Tulane University, Department of Chemistry, New Orleans, Louisiana.
Title: Synthesis and Antitumor Properties of Pyrimidoazepine-Based Tetrahydrofolic Acid Derivatives.
18. November 19, 1998: Auburn University, Department of Chemistry, Auburn, Alabama. Title: Synthesis and Antitumor Properties of Pyrimidoazepine-BasedTetrahydrofolic Acid Derivatives.
17. October 26, 1998: Lyon College, Chemistry Department, Batesville, Arkansas. Title: The Role of Organic Chemistry in Drug Discovery: A Personal Perspective.
16. September 14, 1998: University of Missouri, Department of Chemistry, St. Louis, Missouri. Title: Synthesis of Pyrimidoazepine-Based Folic Acid Derivatives as Potential Antitumor Agents.
15. July 1, 1998: Gordon Research Conference on Heterocyclic Compounds, Salve Regina University, Newport, Rhode Island. Title: Synthesis and Antitumor Properties of Pyrimidoazepine-Based Tetrahydrofolic Acid Derivatives.
14. May 8, 1998: Louisiana State University, Department of Chemistry, Baton Rough, Louisiana.
Title: Synthesis of Pyrimidoazepine-Based Folic Acid Derivatives as Potential Antitumor Agents.
13. January 28, 1998: Austin Peay State University, Science Department, Clarksville, Tennessee.
Title: The Role of Organic Chemistry in Drug Discovery: A Personal Perspective.
12. January 12, 1998: American Cyanamid Company, Agricultural Research Division, Princeton, New Jersy. Title: Synthesis of Pyrimidoazepine-Based Folic Acid Derivatives as Potential Antitumor Agents.
11. October 30, 1997: The University of Arkansas at Pine Bluff, Research Center. Title: Synthesis of Pyrimidoazepine-Based Folic Acid Derivatives as Potential Antitumor Agents.
10. September 11, 1997: J. W. Buser, M. K. Chaguturu, P. A. Cruickshank, T. G. Cullen, R. V. Dargar, J. A. Dybas, J. J. Fiordeliso, R. N. Henrie II, F. L. Marek, A. C. Lew, A. C. Oliphant, G. T. Payne, C. J. Peake, E. L. Plummer, M. J. Plummer, P. S. Ray, D. A. Shook, M. A. Walsh, J. M. Wierenga, 5-Substituted 2,4-Diaminopyrimidines as Insecticides," American Chemical Society, Division of Agrochemicals, 214th National Meeting, Las Vegas, NV. Paper no. 143.
9. May 19, 1997: American Association of Pharmaceutical Scientists 1997 Midwest Regional Meeting, Rosemont Conference Center, Chicago, IL. Title: Synthesis of Pyrimidoazepine-Based Folic Acid Derivatives as Potential Antitumor Agents.
8. April 16, 1997: M. W. Read, M. L. Miller and P. S. Ray, "Synthesis and Antitumor Properties of Pyrimidoazepine-Based Tetrahydrofolic Acid Derivatives," 213th American Chemical Society National
7. March 31, 1997: Murray State University, Department of Chemistry, Murray, Kentucky. Title: Synthesis of Pyrimidoazepine-Based Folic Acid Derivatives as Potential Antitumor Agents.
6. March 18, 1997: University of Mississippi, School of Pharmacy, Oxford. Title: Synthesis of Pyrimidoazepine-Based Folic Acid Derivatives as Potential Antitumor Agents.
Meeting, San Francisco, Calif., Division of Medicinal Chemistry, Paper no. 298.
5. December 30, 1995: M. L. Miller, M. W. Read, and P. S. Ray, "Progress toward the Synthesis of Pyrimidoazepine Based Folic Acid Derviatives as Potential Antitumor Agents," 47th Southeast/51st Southwest Joint Regional Meeting of American Chemical Society, The Peabody Hotel, Memphis, TN. Paper no. 456.
4. November 3, 1995: M. L. Miller, M. W. Read, and P. S. Ray, "Progress toward the Synthesis of Pyrimidoazepine Based Folic Acid Derviatives as Potential Antitumor Agents," 30th American Chemical Society Midwest Regional Meeting, Holiday Inn, Joplin, MO. Paper no. 123.
3. June 13, 1995: M. L. Miller and P. S. Ray, "An Intramolecular 1,3-Dipolar Cycloaddition Route to a Pyrimidoazepinone Derivative. A Potentially Useful Intermediate Towards the Synthesis of Pyrimidoazepine Based Folic Acid Derivatives," 34th National Organic Symposium, The College of William and Mary, Williamsburg, VA. Paper no. 221.
2. January 1993: Memphis State University, Department of Chemistry, Memphis, Tennessee. Title: A Inverse Electron Demand Diels-Alder Approach to Pyridoacridine Alkaloids
1. January 1993: Florida International University, Department of Chemistry, Miami, Florida. Title: A Inverse Electron Demand Diels-Alder Approach to Pyridoacridine Alkaloids
Student Presentations at National and Regional Meetings (presenter underlined)
32. April 6, 2006: Shacklady, Danielle; Frick, Morin; Denton, Elizabeth; Ray, Partha S. “Progress towards the synthesis of pyrimidodiazepine-based folates as potential inhibitors of glycinamide ribonucleotide formyltransferase”, National Conference for Undergraduate Research (NCUR), University of North Carolina, Asheville, North Carolina.
31. December 3, 2005: Shacklady, Danielle; Frick, Morin; Denton, Elizabeth; Ray, Partha S. “Progress towards the synthesis of pyrimidodiazepine-based folates as potential inhibitors of glycinamide ribonucleotide formyltransferase”, overall winner ($1,000 first prize) for oral presentation at the Southeastern Conference on Undergraduate Research at Emory (SCURE), Emory University, Atlanta, Georgia.
30. November 2, 2005: Shacklady, Danielle; Frick, Morin; Denton, Elizabeth; Ray, Partha S. “Progress towards the synthesis of pyrimidodiazepine-based folates as potential inhibitors of glycinamide ribonucleotide formyltransferase”, 57th Southeast/61st Southwest Joint Regional Meeting of the American Chemical Society, Memphis, Tennessee.
29. August 29, 2005: Danielle Shacklady, Morin M. Frick, Elizabeth B. Denton, and Partha S. Ray, “Progress Towards the Synthesis of Pyrimidodiazepine-based Folates as Potential Inhibitors of Glycinamide Ribonucleotide Formyltransferase”, 230th National American Chemical Society Meeting, Division of Chemical Education, Washington, D.C. Paper no. 211.
28. April 7, 2005: Jesse McAtee, “Progress Towards Synthetic Routes to Pyrimidodiazepine-based Folates”, National Conference for Undergraduate Research, Lexington, Virginia.
27. February 25, 2005: Jesse McAtee, “Progress Towards Synthetic Routes to Pyrimidodiazepine-based Folates”, 2005 Georgia Collegiate Honors Council Meeting, Clayton College and State University, Morrow, GA.
26. November 13, 2004: Noah Huddleston, Jeffrey Gaulding, Jesse McAtee, Holley Jeter, and Partha Ray, “Synthesis of a Useful Pyrimidodiazepine Intermediate for the Preparation of Potential Antitumor Agents”, Antitumor Agents”, 56th Southeast Regional Meeting of the American Chemical Society, Durham, North Carolina. Paper no. 796.
25. November 13, 2004: Jesse McAtee, Holly Jeter, Jonathan Meyer, Noah Huddleston, Jessica Harris, Hang Nguyen, and Partha Ray, “Synthesis of a Useful Pyrimidodiazepine Intermediate: Preparation of Potential Antitumor Agents”, National Collegiate Honors Society Conference, New Orleans, Louisiana.
24. March 29, 2004: Noah Huddleston, Jessica Harris, Hang Nguyen, and Partha Ray, “Synthesis of a Useful Pyrimidodiazepine Intermediate for the Preparation of Potential Antitumor Agents”, 227th National American Chemical Society Meeting, Division of Chemical Education, Anaheim, California. Paper no. 509.
23. November 16, 2003: Noah Huddleston, Jessica Harris, Hang Nguyen, and Partha Ray, “Synthesis of a Useful Pyrimidodiazepine Intermediate for the Preparation of Potential Antitumor Agents”, 55th Southeast Regional Meeting of the American Chemical Society, Atlanta, Georgia. Paper no. 1051.
22. November 16, 2003: Joseph Chambers, Bryan Eaves, Danny Parker, Partha Ray, and Spencer Slattery, “Substituent Effects on Redox and Spin State Properties of Iron(II) and Cobalt(II) Bis-Terpyridyl Complexes,” 55th Southeast Regional Meeting of the American Chemical Society, Atlanta, Georgia. Paper no. 984.
21. November 15, 2002: Partha S. Ray, Daniel L. Parker, Susan A. Hughes, and Daniel P. Parker, “An Unexpected Dimer Formation From a 4-(2-Amino-ethylamino)-5-formylpyrimidine Intermediate,” 54th Southeast Regional Meeting of the American Chemical Society, Charleston, South Carolina. Paper no. 721.
20. April 8, 2002: Daniel L. Parker, Spencer J. Slattery, and Partha S. Ray, “Development of Synthetic Methods to Electron-Deficient 4’-Terpyridines,” 223rd National American Chemical Society Meeting, Division of Chemical Education, Orlando, Florida. Paper no. 713.
19. April 8, 2002: Daniel P. Parker, Susan A. Hughes, Daniel L. Parker, and Partha S. Ray, “Studies Towards the Synthesis of a Pyrimidodiazepine-Based Folate as a Potential Inhibitor of Glycinamide Ribonucleotide Formyltransferase,” 223rd National American Chemical Society Meeting, Division of Chemical Education, Orlando, Florida. Paper no. 680.
18. September 23, 2001: D. L. Parker, J. P. Lee, S. J. Slattery, and P. S. Ray, “Development of Synthetic Methods to Electron Deficient 4’-Terpyridines” 53rd Southeast Regional Meeting of the American Chemical Society, Savannah, Georgia; Paper no. 664.
17. October 19, 1999: B. Ayida and P. S. Ray, “Studies Toards the Synthesis of Pyrimidodiazepine-Based Tetrahydrofolic Acid Derivatives as Potential Antitumor Agents”. American Chemical Society Southeast Regional Meeting, Knoxville, Tennessee. Paper no. 137.
16. August 23, 1999: B. Ayida and P. S. Ray, “Studies Toards the Synthesis of Pyrimidodiazepine-Based Tetrahydrofolic Acid Derivatives as Potential Antitumor Agents”. 218th National American Chemical Society Meeting, Division of Medicinal Chemistry, New Orleans, Louisiana. Paper no. 56.
15. August 25, 1998: M. L. Miller, M. W. Read, and P. S. Ray, “Synthesis and Antitumor Properties of Pyrimidoazepine-Based Tetrahydrofolic Acid Derivatives”. 216th American Chemical Society Meeting, Division of Medicinal Chemistry, Boston, Massachusetts. Paper no. 199.
14. June 15, 1998: M. L. Miller, M. W. Read, and P. S. Ray, “Synthesis and Antitumor Properties of Pyrimidoazepine-Based Tetrahydrofolic Acid Derivatives”. 26th National Medicinal Chemistry Symposia, Virginia Commonwealth University, Richmond, Virginia.
13. October 2, 1997: M. W. Read and P. S. Ray, "Progress Towards the Synthesis of Pyrimidoazepine-Based Tetrahydrofolic Acid Derivatives as Potential Inhibitors of Glycinamide Ribonucleotide Formyltransferase: An Approach from Caprolactam," American Chemical Society Southwest Regional Meeting, Tulsa, Oklahoma. Paper no. 110.
12. October 2, 1997: M. L. Miller and P. S. Ray, "Synthesis of Pyrimidoazepine-Based Tetrahydrofolic Acid Derivatives as Potential Inhibitors of Glycinamide Ribonucleotide Formyltransferase: A 1,3-Dipolar Cycloaddition Approach," American Chemical Society Southwest Regional Meeting, Tulsa, Oklahoma. Paper no. 109.
11. October 2, 1997: K. L. Smith and P. S. Ray, "Progress Towards the Synthesis of Pyridoacridine and Azaoxoaporphine Alkaloids via Inverse Electron Demand Diels-Alder Chemistry," American Chemical Society Southwest Regional Meeting, Tulsa, Oklahoma. Paper no. 107.
10. June 24, 1997: M. L. Miller and P. S. Ray, "Synthesis of Pyrimidoazepine-Based Tetrahydrofolic Acid Derivatives as Potential Inhibitors of Glycinamide Ribonucleotide Formyltransferase: A 1,3-Dipolar Cycloaddition Approach," 35th National Organic Symposium, San Antonio, TX. Paper no. T201.
9. June 21, 1997: K. L. Smith and P. S. Ray, "Progress Towards the Synthesis of Pyridoacridine and Azaoxoaporphine Alkaloids via Inverse Electron Demand Diels-Alder Chemistry," 35th National Organic Symposium, San Antonio, TX. Paper no. S19.
8. June 21, 1997: M. W. Read and P. S. Ray, "Progress Towards the Synthesis of Pyrimidoazepine-Based Tetrahydrofolic Acid Derivatives as Potential Inhibitors of Glycinamide Ribonucleotide Formyltransferase: An Approach from Caprolactam," 35th National Organic Symposium, San Antonio, TX. Paper no. S61.
7. June, 1997: N. A. Ayers, O. W. Nadeau, M. W. Read, P. S. Ray, and G. M. Carlson, "Chemical Crosslinking of Phosphorlyase-b Kinase by the Novel Crosslinker, 4-Phenyl-1,2,4-triazoline-3,5-dione," 17th International Congress of Biochemistry and Molecular Biology and 1997 Annual meeting of the American Society for Biochemistry and Molecular Biology.
6. November 11, 1996: M. L. Miller and P. S. Ray, "Synthesis of Pyrimidoazepine-Based Folic Acid Derivatives as Potential Antitumor Agents: A 1,3-Dipolar Cycloaddition Approach," 48th American Chemical Society Southeast Regional Meeting, Hyatt Regency Hotel, Greenville, S.C. Paper no. 270.
5. November 11, 1996: M. W. Read and P. S. Ray, "Progress toward the Synthesis of Pyrimidoazepine-Based Folic Acid Derivatives as Potential Antitumor Agents: An Approach from Caprolactam," 48th American Chemical Society Southeast Regional Meeting, Hyatt Regency Hotel, Greenville, S.C. Paper no. 271.
4. October 17, 1996: M. W. Read and P. S. Ray,"Progress toward the Synthesis of Pyrimidoazepine-Based Folic Acid Derivatives as Potential Antitumor Agents: An Approach from Caprolactam," 52nd American Chemical Society Southwest Regional Meeting, Adam's Mark Hotel, Houston, TX. Paper no.108.
3. October 17, 1996: M. L. Miller and P. S. Ray, "Synthesis of Pyrimidoazepine-Based Folic Acid Derivatives as Potential Antitumor Agents: A 1,3-Dipolar Cycloaddition Approach," 52nd American Chemical Society Southwest Regional Meeting, Adam's Mark Hotel, Houston, TX. Paper no. 109.
2. April 27, 1996: M. W. Read and P. S. Ray, "Progress toward the Synthesis of Pyrimidoazepine Based Folic Acid Derviatives as Potential Antitumor Agents," 19th Annual Area Collegiate Chemistry Meeting, UT Martin, Martin, TN.
1. April 27, 1996: M. L. Miller and P. S. Ray, "An Intramolecular 1,3-Dipolar Cycloaddition Route to a Pyrimidoazepinone Derivative. A Potentially Useful Intermediate Towards the Synthesis of Pyrimidoazepine Based Folic Acid Derivatives," 19th Annual Area Collegiate Chemistry Meeting, UT Martin, Martin, TN.
Professional Membership/Service
Member of the American Chemical Society since 1985. Member of the following divisions:
Organic Chemistry, Medicinal Chemistry, Agrochemical, and Agriculture and Food Chemistry.
Grant Reviewer for National Science Foundation, and Petroleum Research Fund (American Chemical Society).
Journal Reviewer for Tetrahedron, Journal of the American Chemical Society, and Heterocyclic Communications.
AGENCY AMOUNT PERIOD
4. National Science Foundation (# 0243921).
REU Site: Research Experiences for Two-Year College Undergraduates in $217,838 Apr 03-Mar 06
Chemistry. Investigator. Gigi B. Ray (PI) and Victoria J. Geisler (co-PI).
2. National Cancer Institute, National Institutes of Health. $95,590 Sept 98-Aug 00
Proposal Title: Pyrimidoazepine-Based Folates as Potential
Antitumor Agents. PI
1. The Elsa U. Pardee Foundation. Proposal Title: The Design and Synthesis $66,046 Jan 97-Dec 98
of Novel Inhibitors of Glycinamide Ribonucleotide Formyltransferase:
Potentially Selective Antitumor Agents. PI